Breakthrough infections in India show high proportion of Delta variant

NEW DELHI, AUG 20 (AGENCIES) | Publish Date: 8/20/2021 12:55:53 PM IST

Breakthrough infections of coronavirus cases comprise a very high proportion of the Delta variant, the INSACOG, a genome sequencing government consortium of laboratories, has said.

The continuing COVID-19 outbreaks across India are attributable to the Delta variant, a susceptible population and reduced vaccine effectiveness in blocking transmission, INSACOG added. However, vaccination continues to be very effective in reducing severe disease and death, and public health measures to reduce transmission and inoculation remain critical, INSACOG stressed in its latest bulletin dated August 16. 

“As of now, sequencing of vaccination breakthroughs in India is also showing a very high proportion of Delta variant. Investigations for any new variants are ongoing,” INSACOG said. 

Of the 30,230 samples of Variants of Concern and Variants of Interest sequenced by INSACOG, 20,324 were of Delta, it said. 

Delta variant is currently driving pandemic across several countries with China and Korea seeing new highs. Korea has reported that new surge is due to Delta plus K417N mutation.

Delta variant resulted in a deadly second wave in the country between March to May that wreaked havoc on health infrastructure, overwhelming hospitals. It infected lakhs and killed thousands. In India, new cases of AY.1, AY.2, AY.3 (Delta Plus) are being seen in July samples from Maharashtra at a frequency of about 1 per cent. However, at this time none of these sub-lineages has been found to have a growth advantage over the Delta parent lineage, it noted. 

According to INSACOG (Indian SARS-CoV2 Genomics Consortium), 61 samples of Delta Plus variants have been detected in the country so far. 

“Delta variant is the major VOC in India at this time. Continuing outbreaks across India are attributable to Delta, a susceptible population, reduced vaccine effectiveness in blocking transmission, and opportunities for transmission,” INSACOG said.

Daily coronavirus cases have seen a significant plunge since the second wave which peaked in May. 

There has been a concern whether an increasing vaccination breakthroughs in India are because of a new variant, INSACOG said.